丝裂霉素C

产地：simga 
货号：M0503 
规格：2MG
中文名：丝裂霉素C(自力霉素) ，丝裂霉素、自力霉素、密吡霉素
英文名：Mitomycin C (MMC) ，Mito-mycin,Mutamycin,Mytomycin,Ametycine,MMC
用途：本品是从头状链霉菌培养液中分离提取的一种广谱抗肿瘤抗生素，对多种癌症有抗癌作用，其作用原理可使细胞的DNA解聚，同时阻碍DNA的复制，从而抑制肿瘤细胞分裂。本品为细胞周期非特异性药物，其抗肿瘤谱较广，作用迅速，但治疗指数不高，毒性较大。临床适用于消化道癌，如胃癌、肠癌、肝癌及胰腺癌等，疗效较好。对肺癌、乳腺癌、宫颈癌及绒毛膜上皮癌等也有效。还可用于恶性淋巴瘤、癌性胸腹腔积液。
说明：
Sigma  M0503 Mitomycin C from Streptomyces caespitosus
powder
CAS Number: 50-07-7
Linear Formula: C15H18N4O5
Molecular Weight: 334.33
Beilstein Registry Number: 7231816
MDL number: MFCD00078109
PubChem Substance ID: 24896555
Description
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Biochem/physiol Actions Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.
Other Notes Vial contains 2 mg mitomycin C and 48 mg NaCl.
Properties
form powder
storage temp. 2-8°C